SARS-like virus cases found

LONDON: A new virus from the same family as SARS which sparked a global alert in September has now killed two people in Saudi Arabia, and total cases there and in Qatar have reached six, the World Health Organisation said.

The U.N. health agency issued an international alert in late September saying a virus previously unknown in humans had infected a Qatari man who had recently been in Saudi Arabia, where another man with the same virus had died.

On Friday it said in an outbreak update that it had registered four more cases and one of the new patients had died.

"The additional cases have been identified as part of the enhanced surveillance in Saudi Arabia (3 cases, including 1 death) and Qatar (1 case)," the WHO said.

The new virus is known as a coronavirus and shares some of the symptoms of SARS, or Severe Acute Respiratory Syndrome, which emerged in China in 2002 and killed around a 10th of the 8,000 people it infected worldwide.

Among the symptoms in the confirmed cases are fever, coughing and breathing difficulties.

Of the six laboratory-confirmed cases reported to WHO, four cases, including the two deaths, are from Saudi Arabia and two cases are from Qatar.

Britain's Health Protection Agency, which helped to identify the new virus in September, said the newly reported case from Qatar was initially treated in October in Qatar but then transferred to Germany, and has now been discharged.

Coronaviruses are typically spread like other respiratory infections, such as flu, travelling in airborne droplets when an infected person coughs or sneezes.

The WHO said investigations were being conducted into the likely source of the infection, the method of exposure, and the possibility of human-to-human transmission of the virus.

"Close contacts of the recently confirmed cases are being identified and followed-up," it said.

It added that so far, only the two most recently confirmed cases in Saudi Arabia were epidemiologically linked - they were from the same family, living in the same household.

"Preliminary investigations indicate that these two cases presented with similar symptoms of illness. One died and the other recovered," the WHO's statement said.

Two other members of the same family also suffered similar symptoms of illness, and one died and the other is recovering. But the WHO said laboratory test results on the fatality were still pending, and the person who is recovering had tested negative for the new coronavirus.

The virus has no formal name, but scientists at the British and Dutch laboratories where it was identified refer to it as "London1_novel CoV 2012".

The WHO urged all its member states to continue surveillance for severe acute respiratory infections.

"Until more information is available, it is prudent to consider that the virus is likely more widely distributed than just the two countries which have identified cases," it said. (Reuters)

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Caffeine-diabetes

NEW YORK: Results of a large new U.S. study confirm that sugary drinks are linked to a heightened risk of developing Type 2 diabetes, but shed little light on whether caffeine helps or hinders the process.

Among more than 100,000 men and women followed for 22 years, those who drank sugar-sweetened drinks were as much as 23 percent more likely to develop diabetes than those who didn't, but the risk was about the same whether the drinks contained caffeine or not. And drinkers of both caffeinated coffee and decaf had slightly lowered diabetes risk.

"We found that caffeine doesn't make a difference at all," said the study's lead author Dr. Frank Hu of Harvard University. "Coffee can be beneficial and the caffeine doesn't appear to have a positive or negative effect on diabetes risk," Hu told Reuters Health.

Numerous past studies have linked regular consumption of soft drinks - both sugar- and artificially-sweetened - to an increased risk of diabetes. Research over the past decade has also suggested that caffeine temporarily prevents the body from processing sugar efficiently. Those who live with diabetes deal with this problem all the time.

That at least suggests that caffeine in conjunction with sweetened drinks might raise diabetes risk even further. However, other research has found a protective effect from coffee and tea, suggesting caffeine does the opposite.

Hu and his coauthors wanted to know if people who regularly drink sugary and caffeinated beverages might only be exaggerating their risk of developing a disease that affects nearly 26 million adults and children, or about eight percent of the U.S. population, according to the American Diabetes Association.

They examined the health habits of 75,000 women and 39,000 men involved in long-term health studies that began in the mid-1980s.

Compared to people who didn't consume sugary drinks, the likelihood of developing diabetes over the years for those who did was higher by 13 percent (caffeinated) or 11 percent (decaffeinated) among women, and by 16 percent (caffeinated) or 23 percent (decaffeinated) among men.

Caffeine-free artificially sweetened drinks were also linked to a slight (six percent) increase in risk among women.

However, coffee drinkers showed slightly lower risk compared to non-drinkers. The chances of developing diabetes were eight percent lower among women, whether they drank decaf or regular coffee, and for men, four percent lower with caffeinated coffee and seven percent lower with decaf.

Hu and his team have used this same dataset, which contains the health habits of mostly white health professionals, to suggest that regular coffee drinking in general is tied to lower diabetes risk.

But past studies, like the current one, have also found that the risk falls even lower if adults drink decaffeinated coffee.

"Our understanding of the body's tolerance to caffeine is not complete," said James Lane of Duke University. Lane has done short-term studies that linked caffeine to a disruption of the body's ability to process glucose, or "blood sugar."

This latest study suggests that people who currently drink sugary beverages could substitute unsweetened coffee or tea - though tea was associated with fewer benefits - instead.

Such advice could be important, since the number of Americans who develop diabetes has steadily increased, according to a study released earlier this month by the U.S. Centers for Disease Control and Prevention.

Diabetes can only be managed, not cured and its side effects range from high blood pressure to debilitating blindness.

"I'm disappointed that they are essentially repeating something they published several years ago. The bit about including sugar sweetened beverages and caffeine's possible interaction with sugar and diabetes does not add something of great value," Lane told Reuters Health.

Others agree more research is necessary to untangle caffeinated coffee's complicated relationship with diabetes risk.

At least one small, randomized two-month-long trial led last year by Rob Martinus van Dam of the National University of Singapore, also a co-author of the current study, found that caffeinated coffee did not seem to affect glucose levels in the blood.

Van Dam told Reuters Health that the next step toward establishing a direct link between caffeinated coffee and reduced diabetes risk would require a much larger study.

"We still don't advise people to start drinking coffee if they do not already," van Dam said.

People who want to lower their risk of developing diabetes could follow advice that has been better substantiated, such as eating large amounts of fruits and vegetables and exercising regularly. (Reuters)

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4D scans show fetuses yawn in the womb

LONDON: Growing into a fully formed human being is a long process, and scientists have found that unborn babies not only hiccup, swallow and stretch in the womb, they yawn too.

Researchers who studied 4D scans of 15 healthy fetuses also said they think yawning is a developmental process which could potentially give doctors a new way to check on a baby's health.

While some scientists have previously suggested that fetuses yawn, others disagree and say it is nothing more than a developing baby opening and stretching its mouth.

But writing in the journal PLOS ONE on Wednesday, British researchers said their study was able to clearly distinguish yawning from "non-yawn mouth opening" based on how long the mouth was open.

The researchers did this by using 4D video footage to examine all the times when fetuses opened their mouths.

Nadja Reissland of Durham University's department of Psychology, who led the study, said the function and importance of yawning in fetuses is still unknown, but the findings suggest it may be linked to fetal development and could provide a further indication of the health of the unborn baby.

"Unlike us, fetuses do not yawn contagiously, nor do they yawn because they are sleepy," she said. "Instead, the frequency of yawning in the womb may be linked to the maturing of the brain early in gestation."

The study was carried out on eight female and seven male fetuses from 24 to 36 weeks gestation. The researchers found that yawning declined from 28 weeks and that there was no significant difference in how often boys and girls yawned. (Reuters)

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New SARS virus

PARIS: A novel strain of the deadly SARS virus that sparked a health scare this year is closely related to a virus found in Asian bats, according to a study published on Tuesday.

Scientists in the Netherlands said they had sequenced the genetic code of a viral sample taken from a 60-year-old man whose death in Jeddah, Saudi Arabia, in June triggered fears that Severe Acute Respiratory Syndrome (SARS) was returning in a new guise.

The new strain, called HCoV-EMC/2012, is part of a viral family called coronavirus, but in a specific category called betacoronavirus.

Its closest known cousins are a strain found in lesser bamboo bats (Tylonycteris pachypus) and another found in Japanese house bats, Pipistrellus abramus.

"The virus is most closely related to viruses in bats in Asia, and there are no human viruses closely related to it," said Ron Fouchier of the prestigious Erasmus Medical Centre in Rotterdam.

"Therefore we speculate that it comes from an animal source," he said, noting that Pipistrellus bats are present in Saudi Arabia and neighbouring countries.

An epidemic of SARS erupted in China in 2002, eventually claiming around 800 deaths in some 30 countries.

Bats were linked with a novel strain of SARS found in 2005. Hong Kong researchers found a natural "reservoir" of it in Chinese horseshoe bats.

Two other men have also fallen sick in the latest SARS episode.

One is a Qatari man who had been in Saudi Arabia and is being treated at a hospital in London.

There is 99.6-99.7 percent similarity between his strain and the virus sequenced in the Netherlands, said Fouchier in a press release.

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